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Anti-FBP2 Antibody

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Anti-FBP2 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-FBP2 Antibody See all FBP2 primary antibodies
Description:	Rabbit polyclonal antibody to FBP2
Specificity:	The antibody detects endogenous levels of total FBP2 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Full length fusion protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Tissue Specificity:	Expressed in skeletal muscle (at protein level).
Sequence Similarities:	Belongs to the FBPase class 1 family.
Cellular Location:	Cell junction. Cytoplasm. Nucleus. Cytoplasm > Myofibril > Sarcomere > Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
Database Links:	Entrez Gene: 8789?Human Omim: 603027?Human SwissProt: O00757?Human Unigene: 61255?Human
Synonyms:	6-bisphosphatase isozyme 2 Antibody 6-bisphosphate 1-phosphohydrolase 2 Antibody D fructose 1 6 bisphosphate 1 phosphohydrolase 2 Antibody D-fructose-1 Antibody F16P2_HUMAN Antibody FBP 2 Antibody FBP2 Antibody FBPase Antibody FBPase 2 Antibody fructose 1 6 bisphosphatase 2 Antibody Fructose 1 6 bisphosphatase isozyme 2 Antibody Fructose-1 Antibody Hexosediphosphatase Antibody MGC142192 Antibody Muscle FBPase Antibody Muscle fructose bisphosphatase Antibody
Information:	Target information shown above is from the UniProt Consortium.